We always love to show off our users amazing work. Empower scientists to enable a more more visual and reachable science. In the post, I will present Christina Hermanrud research thesis for her doctoral degree entitled Immunogenicity of Biopharmaceuticals in Chronic Inflammatory diseases. Dr. Hermanrud is a neuroscientist from Karolinska Institutet in Sweden. Her research focuses on chronic inflammatory diseases like multiple sclerosis (MS) and rheumatoid arthritis (RA) where genetic and environmental factors influence the pathogenesis. Dr. Hermanrud thesis incluide five studies to evaluate endogenous immune processes affected
Multiple sclerosis (MS) and rheumatoid arthritis (RA) are chronic inflammatory diseases where genetic and environmental factors influence the pathogenesis. MS is a disease of the central nervous system, while RA primarily affects the joints. Biopharmaceuticals such as interferon beta (IFNβ) and tumor necrosis factor-alpha (TNF-α) inhibitors are widely used treatments to achieve a reduction in disease activity in people with MS and RA respectively. Over time, however, some of the treated patients develop anti-drug antibodies (ADA) or neutralizing ADA (NAb) that can reduce or abrogate the drug efficacy and subsequently lead to loss of clinical response.
She is also a Mind the Graph user and created her illustrations using the platform. That makes us very proud, so I will share some of her creations to inspire and help other scientists to create their own illustrations. Dr. Hermanrud used the graphical abstracts she made at Mind the Graph in a way to complement and illustrate main points of his research.
Inspirations for who is writing a thesis
She created illustrations to show immune complex formation, cell signaling pathways, drug administration and leukocytes migration:
Also, she created graphical abstracts to illustrate the assays used to measure neutralizing anti-drug antibody (NAb). These assays were based on the antibodies ability to antagonize the biopharmaceutical in for example the cellular response of the drug.
Congratulations Dr. Hermanrud and thank you for using Mind the Graph!
And if you want to learn about how to make amazing graphical abstracts of your own, here are a couple posts that can help you:
If you are writing a thesis and want to create your own illustrations, start now:
Also published on Medium.